Cargando…

Peiminine Reduces ARTS-Mediated Degradation of XIAP by Modulating the PINK1/Parkin Pathway to Ameliorate 6-Hydroxydopamine Toxicity and α-Synuclein Accumulation in Parkinson’s Disease Models In Vivo and In Vitro

Parkinson’s disease (PD) is a degenerative disease that can cause motor, cognitive, and behavioral disorders. The treatment strategies being developed are based on the typical pathologic features of PD, including the death of dopaminergic (DA) neurons in the substantia nigra of the midbrain and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsu, Yu-Ling, Hung, Huey-Shan, Tsai, Chia-Wen, Liu, Shih-Ping, Chiang, Yu-Ting, Kuo, Yun-Hua, Shyu, Woei-Cherng, Lin, Shinn-Zong, Fu, Ru-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549710/
https://www.ncbi.nlm.nih.gov/pubmed/34638579
http://dx.doi.org/10.3390/ijms221910240