Cargando…
A general approach to 2,2-disubstituted indoxyls: total synthesis of brevianamide A and trigonoliimine C
The indoxyl unit is a common structural motif in alkaloid natural products and bioactive compounds. Here, we report a general method that transforms readily available 2-substituted indoles into 2,2-disubstituted indoxyls via nucleophile coupling with a 2-alkoxyindoxyl intermediate and showcase its u...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549782/ https://www.ncbi.nlm.nih.gov/pubmed/34760160 http://dx.doi.org/10.1039/d1sc03533a |