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Molecular basis for acyl carrier protein–ketoreductase interaction in trans-acyltransferase polyketide synthases
The biosynthesis of polyketides by type I modular polyketide synthases (PKS) relies on co-ordinated interactions between acyl carrier protein (ACP) domains and catalytic domains within the megasynthase. Despite the importance of these interactions, and their implications for biosynthetic engineering...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549798/ https://www.ncbi.nlm.nih.gov/pubmed/34760152 http://dx.doi.org/10.1039/d1sc03478b |