Dithiolane quartets: thiol-mediated uptake enables cytosolic delivery in deep tissue

The cytosolic delivery of various substrates in 3D multicellular spheroids by thiol-mediated uptake is reported. This is important because most orthodox systems, including polycationic cell-penetrating peptides, fail to deliver efficiently into deep tissue. The grand principles of supramolecular che...

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Detalles Bibliográficos
Autores principales: Martinent, Rémi, Tawffik, Salman, López-Andarias, Javier, Moreau, Dimitri, Laurent, Quentin, Matile, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549803/
https://www.ncbi.nlm.nih.gov/pubmed/34760179
http://dx.doi.org/10.1039/d1sc04828g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549803/
https://www.ncbi.nlm.nih.gov/pubmed/34760179
http://dx.doi.org/10.1039/d1sc04828g

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