Cargando…

Characterization of the T4 gp32–ssDNA complex by native, cross-linking, and ultraviolet photodissociation mass spectrometry

Protein–DNA interactions play crucial roles in DNA replication across all living organisms. Here, we apply a suite of mass spectrometry (MS) tools to characterize a protein-ssDNA complex, T4 gp32·ssDNA, with results that both support previous studies and simultaneously uncover novel insight into thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Blevins, Molly S., Walker, Jada N., Schaub, Jeffrey M., Finkelstein, Ilya J., Brodbelt, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549804/
https://www.ncbi.nlm.nih.gov/pubmed/34760161
http://dx.doi.org/10.1039/d1sc02861h