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Monoclonal Antibodies in the Management of Familial Hypercholesterolemia: Focus on PCSK9 and ANGPTL3 Inhibitors

PURPOSE OF REVIEW: Familial hypercholesterolemia (FH) is a monogenic disorder characterized by high plasma levels of low-density lipoprotein cholesterol (LDL-C) since birth and a high risk of premature cardiovascular disease. The genetic defect is carried in only one allele in heterozygous FH (HeFH)...

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Detalles Bibliográficos
Autores principales: Pirillo, Angela, Catapano, Alberico L., Norata, Giuseppe D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549899/
https://www.ncbi.nlm.nih.gov/pubmed/34698927
http://dx.doi.org/10.1007/s11883-021-00972-x