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Monoclonal Antibodies in the Management of Familial Hypercholesterolemia: Focus on PCSK9 and ANGPTL3 Inhibitors
PURPOSE OF REVIEW: Familial hypercholesterolemia (FH) is a monogenic disorder characterized by high plasma levels of low-density lipoprotein cholesterol (LDL-C) since birth and a high risk of premature cardiovascular disease. The genetic defect is carried in only one allele in heterozygous FH (HeFH)...
Autores principales: | Pirillo, Angela, Catapano, Alberico L., Norata, Giuseppe D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549899/ https://www.ncbi.nlm.nih.gov/pubmed/34698927 http://dx.doi.org/10.1007/s11883-021-00972-x |
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