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B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells

Malaria, caused by parasites of the Plasmodium genus, is responsible for significant morbidity and mortality globally. Chronic Plasmodium falciparum exposure affects the B cell compartment, leading to the accumulation of atypical memory B cells (atMBCs). IgM-positive (IgM(+)) and IgG(+) atMBCs have...

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Detalles Bibliográficos
Autores principales: Braddom, Ashley E., Bol, Sebastiaan, Gonzales, S. Jake, Reyes, Raphael A., Musinguzi, Kenneth, Nankya, Felistas, Ssewanyana, Isaac, Greenhouse, Bryan, Bunnik, Evelien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550134/
https://www.ncbi.nlm.nih.gov/pubmed/34523978
http://dx.doi.org/10.1128/mSphere.00726-21