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B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells
Malaria, caused by parasites of the Plasmodium genus, is responsible for significant morbidity and mortality globally. Chronic Plasmodium falciparum exposure affects the B cell compartment, leading to the accumulation of atypical memory B cells (atMBCs). IgM-positive (IgM(+)) and IgG(+) atMBCs have...
Autores principales: | Braddom, Ashley E., Bol, Sebastiaan, Gonzales, S. Jake, Reyes, Raphael A., Musinguzi, Kenneth, Nankya, Felistas, Ssewanyana, Isaac, Greenhouse, Bryan, Bunnik, Evelien M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550134/ https://www.ncbi.nlm.nih.gov/pubmed/34523978 http://dx.doi.org/10.1128/mSphere.00726-21 |
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