Maintenance of genome sequence integrity in long- and short-lived rodent species

DNA mutations in somatic cells have been implicated in the causation of aging, with longer-lived species having a higher capacity to maintain genome sequence integrity than shorter-lived species. In an attempt to directly test this hypothesis, we used single-cell whole-genome sequencing to analyze s...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Dong, Xiao, Tian, Xiao, Lee, Moonsook, Ablaeva, Julia, Firsanov, Denis, Lee, Sang-Goo, Maslov, Alexander Y., Gladyshev, Vadim N., Seluanov, Andrei, Gorbunova, Vera, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550225/
https://www.ncbi.nlm.nih.gov/pubmed/34705500
http://dx.doi.org/10.1126/sciadv.abj3284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550225/
https://www.ncbi.nlm.nih.gov/pubmed/34705500
http://dx.doi.org/10.1126/sciadv.abj3284

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