Brain inflammation triggers macrophage invasion across the blood-brain barrier in Drosophila during pupal stages

The nervous system is shielded from circulating immune cells by the blood-brain barrier (BBB). During infections and autoimmune diseases, macrophages can enter the brain where they participate in pathogen elimination but can also cause tissue damage. Here, we establish a Drosophila model to study ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Winkler, Bente, Funke, Dominik, Benmimoun, Billel, Spéder, Pauline, Rey, Simone, Logan, Mary A., Klämbt, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550232/
https://www.ncbi.nlm.nih.gov/pubmed/34705495
http://dx.doi.org/10.1126/sciadv.abh0050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550232/
https://www.ncbi.nlm.nih.gov/pubmed/34705495
http://dx.doi.org/10.1126/sciadv.abh0050

Ejemplares similares