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Brain inflammation triggers macrophage invasion across the blood-brain barrier in Drosophila during pupal stages
The nervous system is shielded from circulating immune cells by the blood-brain barrier (BBB). During infections and autoimmune diseases, macrophages can enter the brain where they participate in pathogen elimination but can also cause tissue damage. Here, we establish a Drosophila model to study ma...
Autores principales: | Winkler, Bente, Funke, Dominik, Benmimoun, Billel, Spéder, Pauline, Rey, Simone, Logan, Mary A., Klämbt, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550232/ https://www.ncbi.nlm.nih.gov/pubmed/34705495 http://dx.doi.org/10.1126/sciadv.abh0050 |
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