Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development

Background: Alterations in plasma protein concentrations in pregnant and postpartum individuals can influence antiretroviral (ARV) pharmacokinetics. Physiologically-based pharmacokinetic (PBPK) models can serve to inform drug dosing decisions in understudied populations. However, development of such...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Sherry, Gockenbach, Mary, Grimstein, Manuela, Sachs, Hari Cheryl, Mirochnick, Mark, Struble, Kimberly, Belew, Yodit, Wang, Jian, Capparelli, Edmund V., Best, Brookie M., Johnson, Tamara, Momper, Jeremiah D., Maharaj, Anil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550258/
https://www.ncbi.nlm.nih.gov/pubmed/34722417
http://dx.doi.org/10.3389/fped.2021.721059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550258/
https://www.ncbi.nlm.nih.gov/pubmed/34722417
http://dx.doi.org/10.3389/fped.2021.721059

Ejemplares similares