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The secondary messenger ppGpp interferes with cAMP-CRP regulon by promoting CRP acetylation in Escherichia coli

The cAMP-CRP regulon coordinates transcription regulation of several energy-related genes, the lac operon among them. Lactose, or IPTG, induces the lac operon expression by binding to the LacI repressor, and releasing it from the promoter sequence. At the same time, the expression of the lac operon...

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Detalles Bibliográficos
Autores principales: Ro, Chunghwan, Cashel, Michael, Fernández-Coll, Llorenç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550359/
https://www.ncbi.nlm.nih.gov/pubmed/34705884
http://dx.doi.org/10.1371/journal.pone.0259067