Allosteric Regulation of 3CL Protease of SARS-CoV-2 and SARS-CoV Observed in the Crystal Structure Ensemble

The 3C-like protease (3CL(pro)) of SARS-CoV-2 is a potential therapeutic target for COVID-19. Importantly, it has an abundance of structural information solved as a complex with various drug candidate compounds. Collecting these crystal structures (83 Protein Data Bank (PDB) entries) together with t...

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Detalles Bibliográficos
Autores principales: Kidera, Akinori, Moritsugu, Kei, Ekimoto, Toru, Ikeguchi, Mitsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550881/
https://www.ncbi.nlm.nih.gov/pubmed/34717972
http://dx.doi.org/10.1016/j.jmb.2021.167324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550881/
https://www.ncbi.nlm.nih.gov/pubmed/34717972
http://dx.doi.org/10.1016/j.jmb.2021.167324

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