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Allosteric Regulation of 3CL Protease of SARS-CoV-2 and SARS-CoV Observed in the Crystal Structure Ensemble
The 3C-like protease (3CL(pro)) of SARS-CoV-2 is a potential therapeutic target for COVID-19. Importantly, it has an abundance of structural information solved as a complex with various drug candidate compounds. Collecting these crystal structures (83 Protein Data Bank (PDB) entries) together with t...
Autores principales: | Kidera, Akinori, Moritsugu, Kei, Ekimoto, Toru, Ikeguchi, Mitsunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550881/ https://www.ncbi.nlm.nih.gov/pubmed/34717972 http://dx.doi.org/10.1016/j.jmb.2021.167324 |
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