Protective Role of microRNA-31 in Acetaminophen-Induced Liver Injury: A Negative Regulator of c-Jun N-Terminal Kinase (JNK) Signaling Pathway

BACKGROUND & AIMS: Sustained c-Jun N-terminal kinase (JNK) activation plays a major role in drug-induced liver injury (DILI). Stress-responsive microRNA-31 (miR-31) has been implicated in regulating different cellular damage, and JNK activation could induce miR-31 expression. However, the regula...

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Detalles Bibliográficos
Autores principales: Zheng, Jianxin, Zhou, Hong, Yang, Taihua, Liu, Jinchuan, Qin, Tian, Gu, Xiangqian, Wu, Ji, Zhang, Yi, Wang, Honglin, Tang, Yuanjia, Xue, Feng, Mao, Yimin, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550922/
https://www.ncbi.nlm.nih.gov/pubmed/34311140
http://dx.doi.org/10.1016/j.jcmgh.2021.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550922/
https://www.ncbi.nlm.nih.gov/pubmed/34311140
http://dx.doi.org/10.1016/j.jcmgh.2021.07.011

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