EOMES is essential for antitumor activity of CD8(+) T cells in chronic lymphocytic leukemia

Genome-wide association studies identified a single-nucleotide polymorphism (SNP) affecting the transcription factor Eomesodermin (EOMES) associated with a significantly increased risk to develop chronic lymphocytic leukemia (CLL). Epigenetic analyses, RNA sequencing, and flow cytometry revealed tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Llaó-Cid, Laura, Roessner, Philipp M., Chapaprieta, Vicente, Öztürk, Selcen, Roider, Tobias, Bordas, Marie, Izcue, Ana, Colomer, Dolors, Dietrich, Sascha, Stilgenbauer, Stephan, Hanna, Bola, Martín-Subero, José Ignacio, Seiffert, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550953/
https://www.ncbi.nlm.nih.gov/pubmed/33731848
http://dx.doi.org/10.1038/s41375-021-01198-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550953/
https://www.ncbi.nlm.nih.gov/pubmed/33731848
http://dx.doi.org/10.1038/s41375-021-01198-1

Ejemplares similares