A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome

Older patients with severe physical trauma are at high risk of developing neuropsychiatric syndromes with global impairment of cognition, attention, and consciousness. We employed a thoracic trauma (TxT) mouse model and thoroughly analyzed age-dependent spatial and temporal posttraumatic alterations...

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Detalles Bibliográficos
Autores principales: Cursano, Silvia, Battaglia, Chiara R., Urrutia-Ruiz, Carolina, Grabrucker, Stefanie, Schön, Michael, Bockmann, Jürgen, Braumüller, Sonja, Radermacher, Peter, Roselli, Francesco, Huber-Lang, Markus, Boeckers, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/
https://www.ncbi.nlm.nih.gov/pubmed/32051550
http://dx.doi.org/10.1038/s41380-020-0659-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/
https://www.ncbi.nlm.nih.gov/pubmed/32051550
http://dx.doi.org/10.1038/s41380-020-0659-y

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