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Clinical and prognostic significance of small paroxysmal nocturnal hemoglobinuria clones in myelodysplastic syndrome and aplastic anemia

In this large single-centre study, we report high prevalence (25%) of, small (<10%) and very small (<1%), paroxysmal nocturnal hemoglobinuria (PNH) clones by high-sensitive cytometry among 3085 patients tested. Given PNH association with bone marrow failures, we analyzed 869 myelodysplastic sy...

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Detalles Bibliográficos
Autores principales: Fattizzo, Bruno, Ireland, Robin, Dunlop, Alan, Yallop, Deborah, Kassam, Shireen, Large, Joanna, Gandhi, Shreyans, Muus, Petra, Manogaran, Charles, Sanchez, Katy, Consonni, Dario, Barcellini, Wilma, Mufti, Ghulam J., Marsh, Judith C. W., Kulasekararaj, Austin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550969/
https://www.ncbi.nlm.nih.gov/pubmed/33664463
http://dx.doi.org/10.1038/s41375-021-01190-9