Cargando…

In vivo targeted DamID identifies CHD8 genomic targets in fetal mouse brain

Genetic studies of autism have revealed causal roles for chromatin remodeling gene mutations. Chromodomain helicase DNA binding protein 8 (CHD8) encodes a chromatin remodeler with significant de novo mutation rates in sporadic autism. However, relationships between CHD8 genomic function and autism-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wade, A. Ayanna, van den Ameele, Jelle, Cheetham, Seth W., Yakob, Rebecca, Brand, Andrea H., Nord, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551073/
https://www.ncbi.nlm.nih.gov/pubmed/34746699
http://dx.doi.org/10.1016/j.isci.2021.103234