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In vivo targeted DamID identifies CHD8 genomic targets in fetal mouse brain
Genetic studies of autism have revealed causal roles for chromatin remodeling gene mutations. Chromodomain helicase DNA binding protein 8 (CHD8) encodes a chromatin remodeler with significant de novo mutation rates in sporadic autism. However, relationships between CHD8 genomic function and autism-r...
Autores principales: | Wade, A. Ayanna, van den Ameele, Jelle, Cheetham, Seth W., Yakob, Rebecca, Brand, Andrea H., Nord, Alex S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551073/ https://www.ncbi.nlm.nih.gov/pubmed/34746699 http://dx.doi.org/10.1016/j.isci.2021.103234 |
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