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Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
Acetylation coordinates many biological processes to ensure cells respond appropriately to nutrients. However, how acetylation regulates lipid surplus-induced inflammation remains poorly understood. Here, we found that a high-fat diet (HFD) enhanced mitochondrial fatty acid β-oxidation, which enhanc...
Autores principales: | Chen, Qiang, Du, Jianlong, Cui, Kun, Fang, Wei, Zhao, Zengqi, Chen, Qiuchi, Mai, Kangsen, Ai, Qinghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551082/ https://www.ncbi.nlm.nih.gov/pubmed/34746707 http://dx.doi.org/10.1016/j.isci.2021.103244 |
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