CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1

CD157/BST-1 (a member of the ADP-ribosyl cyclase family) is expressed at variable levels in 97% of patients with acute myeloid leukemia (AML), and is currently under investigation as a target for antibody-based immunotherapy. We used peripheral blood and bone marrow samples from patients with AML to...

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Detalles Bibliográficos
Autores principales: Yakymiv, Yuliya, Augeri, Stefania, Bracci, Cristiano, Marchisio, Sara, Aydin, Semra, D’Ardia, Stefano, Massaia, Massimo, Ferrero, Enza, Ortolan, Erika, Funaro, Ada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551154/
https://www.ncbi.nlm.nih.gov/pubmed/34707185
http://dx.doi.org/10.1038/s41598-021-00733-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551154/
https://www.ncbi.nlm.nih.gov/pubmed/34707185
http://dx.doi.org/10.1038/s41598-021-00733-5

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