Endocytic BDNF secretion regulated by Vamp3 in astrocytes

Brain-derived neurotrophic factor (BDNF) regulates diverse brain functions via TrkB receptor signaling. Due to the expression of TrkB receptors, astrocytes can internalize extracellular BDNF proteins via receptor-mediated endocytosis. Endocytosed BDNF can be re-secreted upon stimulation, but the mol...

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Detalles Bibliográficos
Autores principales: Han, Jeongho, Yoon, Sungryeong, Park, Hyungju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551197/
https://www.ncbi.nlm.nih.gov/pubmed/34707216
http://dx.doi.org/10.1038/s41598-021-00693-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551197/
https://www.ncbi.nlm.nih.gov/pubmed/34707216
http://dx.doi.org/10.1038/s41598-021-00693-w

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