Genetic re-direction of canine primary T cells for clinical trial use in pet dogs with spontaneous cancer

Immunocompetent pet dogs develop spontaneous, human-like cancers, representing a parallel patient population for the investigation of chimeric antigen receptor (CAR) therapies. We have optimized a retrovirus-based protocol to efficiently CAR transduce primary T cells from healthy and tumor-bearing d...

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Detalles Bibliográficos
Autores principales: Rotolo, Antonia, Atherton, Matthew J., Kasper, Brian T., Haran, Kumudhini P., Mason, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551231/
https://www.ncbi.nlm.nih.gov/pubmed/34746864
http://dx.doi.org/10.1016/j.xpro.2021.100905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551231/
https://www.ncbi.nlm.nih.gov/pubmed/34746864
http://dx.doi.org/10.1016/j.xpro.2021.100905

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