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High accumulation of Mx2 renders limited multiplication of oncolytic herpes simplex virus-1 in human tumor cells
Increasing studies demonstrated that oncolytic activities of oHSV-1 are limited to the capacity of virus replicating in tumors. In order to potentiate the oHSV-1 oncolytic activity and expand the application of oHSV-1 treatment in multiple types of tumors, it is critical to explore the potential fac...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551283/ https://www.ncbi.nlm.nih.gov/pubmed/34707174 http://dx.doi.org/10.1038/s41598-021-00691-y |