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High accumulation of Mx2 renders limited multiplication of oncolytic herpes simplex virus-1 in human tumor cells

Increasing studies demonstrated that oncolytic activities of oHSV-1 are limited to the capacity of virus replicating in tumors. In order to potentiate the oHSV-1 oncolytic activity and expand the application of oHSV-1 treatment in multiple types of tumors, it is critical to explore the potential fac...

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Detalles Bibliográficos
Autores principales: Ren, Yong, Chen, Meiling, Wu, Guangxian, Ji, Dongmei, Zhou, Grace Guoying, Ren, Pei-Gen, Fu, Wenmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551283/
https://www.ncbi.nlm.nih.gov/pubmed/34707174
http://dx.doi.org/10.1038/s41598-021-00691-y