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TGF-β regulation of the uPA/uPAR axis modulates mesothelial-mesenchymal transition (MesoMT)

Pleural fibrosis (PF) is a chronic and progressive lung disease which affects approximately 30,000 people per year in the United States. Injury and sustained inflammation of the pleural space can result in PF, restricting lung expansion and impairing oxygen exchange. During the progression of pleura...

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Detalles Bibliográficos
Autores principales: Logan, Ranisha, Jeffers, Ann, Qin, Wenyi, Owens, Shuzi, Chauhan, Prashant, Komatsu, Satoshi, Ikebe, Mitsuo, Idell, Steven, Tucker, Torry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551303/
https://www.ncbi.nlm.nih.gov/pubmed/34707211
http://dx.doi.org/10.1038/s41598-021-99520-5