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Molecular characterization of hematopoietic stem cells after in vitro amplification on biomimetic 3D PDMS cell culture scaffolds

Hematopoietic stem cell (HSC) transplantation is successfully applied since the late 1950s. However, its efficacy can be impaired by insufficient numbers of donor HSCs. A promising strategy to overcome this hurdle is the use of an advanced ex vivo culture system that supports the proliferation and,...

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Detalles Bibliográficos
Autores principales: Marx-Blümel, Lisa, Marx, Christian, Sonnemann, Jürgen, Weise, Frank, Hampl, Jörg, Frey, Jessica, Rothenburger, Linda, Cirri, Emilio, Rahnis, Norman, Koch, Philipp, Groth, Marco, Schober, Andreas, Wang, Zhao-Qi, Beck, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551314/
https://www.ncbi.nlm.nih.gov/pubmed/34707135
http://dx.doi.org/10.1038/s41598-021-00619-6