Divergent leukaemia subclones as cellular models for testing vulnerabilities associated with gains in chromosomes 7, 8 or 18

Haematopoietic malignancies are frequently characterized by karyotypic abnormalities. The development of targeted drugs has been pioneered with compounds against gene products of fusion genes caused by chromosomal translocations. While polysomies are equally frequent as translocations, for many of t...

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Detalles Bibliográficos
Autores principales: Maher, Michael, Diesch, Jeannine, Le Pannérer, Marguerite-Marie, Cabezón, Marta, Mallo, Mar, Vergara, Sara, Méndez López, Aleix, Mesa Tudel, Alba, Solé, Francesc, Sorigue, Marc, Zamora, Lurdes, Granada, Isabel, Buschbeck, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551338/
https://www.ncbi.nlm.nih.gov/pubmed/34707142
http://dx.doi.org/10.1038/s41598-021-00623-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551338/
https://www.ncbi.nlm.nih.gov/pubmed/34707142
http://dx.doi.org/10.1038/s41598-021-00623-w

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