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Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice

Noncommunicable diseases (NCDs) account for over 70% of deaths world-wide. Previous work has linked NCDs such as type 2 diabetes (T2D) to disruption of chromatin regulators. However, the exact molecular origins of these chronic conditions remain elusive. Here, we identify the H4 lysine 16 acetyltran...

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Detalles Bibliográficos
Autores principales: Pessoa Rodrigues, Cecilia, Chatterjee, Aindrila, Wiese, Meike, Stehle, Thomas, Szymanski, Witold, Shvedunova, Maria, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551339/
https://www.ncbi.nlm.nih.gov/pubmed/34707105
http://dx.doi.org/10.1038/s41467-021-26277-w