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Venetoclax imparts distinct cell death sensitivity and adaptivity patterns in T cells

BH3 mimetics are increasingly used as anti-cancer therapeutics either alone or in conjunction with other chemotherapies. However, mounting evidence has also demonstrated that BH3 mimetics modulate varied amounts of apoptotic signaling in healthy immune populations. In order to maximize their clinica...

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Detalles Bibliográficos
Autores principales: Ludwig, Lindsey M., Hawley, Katrina M., Banks, David B., Thomas-Toth, Anika T., Blazar, Bruce R., McNerney, Megan E., Leverson, Joel D., LaBelle, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551340/
https://www.ncbi.nlm.nih.gov/pubmed/34707089
http://dx.doi.org/10.1038/s41419-021-04285-4