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Protein Kinase CK1α Sustains B-Cell Receptor Signaling in Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL) is still an incurable B-cell malignancy characterized by poor prognosis and frequent relapses. B Cell Receptor (BCR) signaling inhibitors, in particular of the kinases BTK and PI3Kγ/δ, have demonstrated clinically meaningful anti-proliferative effects in B cell tumors. How...

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Detalles Bibliográficos
Autores principales: Manni, Sabrina, Fregnani, Anna, Quotti Tubi, Laura, Spinello, Zaira, Carraro, Marco, Scapinello, Greta, Visentin, Andrea, Barilà, Gregorio, Pizzi, Marco, Dei Tos, Angelo Paolo, Vianello, Fabrizio, Zambello, Renato, Gurrieri, Carmela, Semenzato, Gianpietro, Trentin, Livio, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551451/
https://www.ncbi.nlm.nih.gov/pubmed/34722279
http://dx.doi.org/10.3389/fonc.2021.733848