SOD1 Mutation Spectrum and Natural History of ALS Patients in a 15-Year Cohort in Southeastern China

Background: Mutations in superoxide dismutase 1 gene (SOD1) are the most frequent high penetrant genetic cause for amyotrophic lateral sclerosis (ALS) in the Chinese population. A detailed natural history of SOD1-mutated ALS patients will provide key information for ongoing genetic clinical trials....

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Detalles Bibliográficos
Autores principales: Chen, Lu-Xi, Xu, Hai-Feng, Wang, Pei-Shan, Yang, Xin-Xia, Wu, Zhi-Ying, Li, Hong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551486/
https://www.ncbi.nlm.nih.gov/pubmed/34721532
http://dx.doi.org/10.3389/fgene.2021.746060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551486/
https://www.ncbi.nlm.nih.gov/pubmed/34721532
http://dx.doi.org/10.3389/fgene.2021.746060

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