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Coexpression of ΔNp63/p40 and TTF1 Within Most of the Same Individual Cells Identifies Life-Threatening NSCLC Featuring Squamous and Glandular Biphenotypic Differentiation: Clinicopathologic Correlations

INTRODUCTION: Double occurrence of TTF1 and ΔNp63/p40 (henceforth, p40) within the same individual cells is exceedingly rare in lung cancer. Little is known on their biological and clinical implications. METHODS: Two index cases immunoreactive for both p40 and TTF1 and nine tumors selected from The...

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Detalles Bibliográficos
Autores principales: Pelosi, Giuseppe, Bulloni, Matteo, Vescio, Martina, Uccella, Silvia, Forest, Fabien, Leone, Giorgia, Barberis, Massimo, Rahal, Daoud, Bossi, Paola, Finzi, Giovanna, Marchiori, Deborah, De Luca, Marco, Sessa, Fausto, Harari, Sergio, Spinelli, Manuela, Viola, Patrizia, Macrì, Paolo, Maria, Stefania, Rizzo, Antonio, Picone, Antonio, Pattini, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551500/
https://www.ncbi.nlm.nih.gov/pubmed/34746884
http://dx.doi.org/10.1016/j.jtocrr.2021.100222