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Structural mapping techniques distinguish the surfaces of fibrillar 1N3R and 1N4R human tau

The rigid core of intracellular tau filaments from Alzheimer's disease (AD), Pick's disease (PiD), and Corticobasal disease (CBD) brains has been shown to differ in their cryo-EM atomic structure. Despite providing critical information on the intimate arrangement of a fraction of htau mole...

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Detalles Bibliográficos
Autores principales: Caroux, Emilie, Redeker, Virginie, Madiona, Karine, Melki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551503/
https://www.ncbi.nlm.nih.gov/pubmed/34592311
http://dx.doi.org/10.1016/j.jbc.2021.101252