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Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats

AIMS: This study aimed to explore the potential protective effect of α-lipoic acid on busulfan-induced pulmonary fibrosis in rats. MAIN METHODS: Eighteen adult male rats were divided into 3 groups; control, busulfan, and busulfan plus α-lipoic acid groups. Lung index ratio, serum level of proinflamm...

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Detalles Bibliográficos
Autores principales: Elhadidy, Mona G., Elmasry, Ahlam, Elsayed, Hassan Reda Hassan, El-Nablaway, Mohammad, Hamed, Shereen, Elalfy, Mahmoud M., Rabei, Mohammed R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551514/
https://www.ncbi.nlm.nih.gov/pubmed/34746462
http://dx.doi.org/10.1016/j.heliyon.2021.e08171