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Path4Drug: Data Science Workflow for Identification of Tissue-Specific Biological Pathways Modulated by Toxic Drugs

The early prediction of drug adverse effects is of great interest to pharmaceutical research, as toxicity is one of the leading reasons for drug attrition. Understanding the cell signaling and regulatory pathways affected by a drug candidate is crucial to the study of drug toxicity. In this study, w...

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Detalles Bibliográficos
Autores principales: Füzi, Barbara, Gurinova, Jana, Hermjakob, Henning, Ecker, Gerhard F., Sheriff, Rahuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551608/
https://www.ncbi.nlm.nih.gov/pubmed/34721010
http://dx.doi.org/10.3389/fphar.2021.708296