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Path4Drug: Data Science Workflow for Identification of Tissue-Specific Biological Pathways Modulated by Toxic Drugs
The early prediction of drug adverse effects is of great interest to pharmaceutical research, as toxicity is one of the leading reasons for drug attrition. Understanding the cell signaling and regulatory pathways affected by a drug candidate is crucial to the study of drug toxicity. In this study, w...
Autores principales: | Füzi, Barbara, Gurinova, Jana, Hermjakob, Henning, Ecker, Gerhard F., Sheriff, Rahuman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551608/ https://www.ncbi.nlm.nih.gov/pubmed/34721010 http://dx.doi.org/10.3389/fphar.2021.708296 |
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