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Sulfation of glycosaminoglycans depends on the catalytic activity of lithium-inhibited phosphatase BPNT2 in vitro

Golgi-resident bisphosphate nucleotidase 2 (BPNT2) is a member of a family of magnesium-dependent, lithium-inhibited phosphatases that share a three-dimensional structural motif that directly coordinates metal binding to effect phosphate hydrolysis. BPNT2 catalyzes the breakdown of 3′-phosphoadenosi...

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Detalles Bibliográficos
Autores principales: Eisele, Brynna S., Luka, Zigmund, Wu, Alice J., Yang, Fei, Hale, Andrew T., York, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551643/
https://www.ncbi.nlm.nih.gov/pubmed/34634304
http://dx.doi.org/10.1016/j.jbc.2021.101293