Homeostatic Function and Inflammatory Activation of Ileal CD8(+) Tissue-Resident T Cells Is Dependent on Mucosal Location

BACKGROUND & AIMS: Tissue-resident memory T (Trm) cells, both of the CD4 and CD8 lineage, have been implicated in disease flares in inflammatory bowel disease. However, data are conflicting regarding the profile of human CD8(+) Trm cells, with studies suggesting both proinflammatory and regulato...

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Detalles Bibliográficos
Autores principales: Lutter, Lisanne, Roosenboom, Britt, Brand, Eelco C., ter Linde, José J., Oldenburg, Bas, van Lochem, Ellen G., Horjus Talabur Horje, Carmen S., van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551698/
https://www.ncbi.nlm.nih.gov/pubmed/34224909
http://dx.doi.org/10.1016/j.jcmgh.2021.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551698/
https://www.ncbi.nlm.nih.gov/pubmed/34224909
http://dx.doi.org/10.1016/j.jcmgh.2021.06.022

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