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Homeostatic Function and Inflammatory Activation of Ileal CD8(+) Tissue-Resident T Cells Is Dependent on Mucosal Location

BACKGROUND & AIMS: Tissue-resident memory T (Trm) cells, both of the CD4 and CD8 lineage, have been implicated in disease flares in inflammatory bowel disease. However, data are conflicting regarding the profile of human CD8(+) Trm cells, with studies suggesting both proinflammatory and regulato...

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Detalles Bibliográficos
Autores principales:	Lutter, Lisanne, Roosenboom, Britt, Brand, Eelco C., ter Linde, José J., Oldenburg, Bas, van Lochem, Ellen G., Horjus Talabur Horje, Carmen S., van Wijk, Femke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551698/ https://www.ncbi.nlm.nih.gov/pubmed/34224909 http://dx.doi.org/10.1016/j.jcmgh.2021.06.022

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