Attenuation of Circulating Trimethylamine N-Oxide Prevents the Progression of Cardiac and Renal Dysfunction in a Rat Model of Chronic Cardiorenal Syndrome

Chronic heart failure (HF) frequently causes progressive decline in kidney function, known as cardiorenal syndrome-2 (CRS2). Current treatment options for CRS2 remain unacceptably limited. Trimethylamine-N-oxide (TMAO), a metabolite of gut microbiota, has recently been implicated in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Zou, Deling, Li, Yanyu, Sun, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551721/
https://www.ncbi.nlm.nih.gov/pubmed/34721039
http://dx.doi.org/10.3389/fphar.2021.751380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551721/
https://www.ncbi.nlm.nih.gov/pubmed/34721039
http://dx.doi.org/10.3389/fphar.2021.751380

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