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Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation

Metformin is an anti-diabetic drug and has anticancer effects on various cancers. Several studies have suggested that metformin reduces cell proliferation and stimulates cell-cycle arrest and apoptosis. However, the definitive molecular mechanism of metformin in the pathophysiological signaling in e...

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Detalles Bibliográficos
Autores principales: Rho, Seung Bae, Byun, Hyun Jung, Kim, Boh-Ram, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551729/
https://www.ncbi.nlm.nih.gov/pubmed/34607979
http://dx.doi.org/10.4062/biomolther.2021.131