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Mitochondrial Contributions in the Genesis of Delayed Afterdepolarizations in Ventricular Myocytes

Mitochondria fulfill the cell’s energy demand and affect the intracellular calcium (Ca(2+)) dynamics via direct Ca(2+) exchange, the redox effect of reactive oxygen species (ROS) on Ca(2+) handling proteins, and other signaling pathways. Recent experimental evidence indicates that mitochondrial depo...

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Detalles Bibliográficos
Autores principales: Pandey, Vikas, Xie, Lai-Hua, Qu, Zhilin, Song, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551757/
https://www.ncbi.nlm.nih.gov/pubmed/34721066
http://dx.doi.org/10.3389/fphys.2021.744023