The miRNA Profile of Inflammatory Colorectal Tumors Identify TGF-β as a Companion Target for Checkpoint Blockade Immunotherapy

Extrinsic factors such as expression of PD-L1 (programmed dealth-ligand 1) in the tumor microenvironment (TME) have been shown to correlate with responses to checkpoint blockade therapy. More recently two intrinsic factors related to tumor genetics, microsatellite instability (MSI), and tumor mutati...

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Detalles Bibliográficos
Autores principales: Bartlett, Bjarne, Gao, Zitong, Schukking, Monique, Menor, Mark, Khadka, Vedbar S., Fabbri, Muller, Fei, Peiwen, Deng, Youping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551827/
https://www.ncbi.nlm.nih.gov/pubmed/34722540
http://dx.doi.org/10.3389/fcell.2021.754507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551827/
https://www.ncbi.nlm.nih.gov/pubmed/34722540
http://dx.doi.org/10.3389/fcell.2021.754507

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