Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity

Multiple agents in the family Filoviridae (filoviruses) are associated with sporadic human outbreaks of highly lethal disease, while others, including several recently identified agents, possess strong zoonotic potential. Although viral glycoprotein (GP)-specific monoclonal antibodies have demonstra...

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Detalles Bibliográficos
Autores principales: Wirchnianski, Ariel S., Wec, Anna Z., Nyakatura, Elisabeth K., Herbert, Andrew S., Slough, Megan M., Kuehne, Ana I., Mittler, Eva, Jangra, Rohit K., Teruya, Jonathan, Dye, John M., Lai, Jonathan R., Chandran, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551868/
https://www.ncbi.nlm.nih.gov/pubmed/34721393
http://dx.doi.org/10.3389/fimmu.2021.729851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551868/
https://www.ncbi.nlm.nih.gov/pubmed/34721393
http://dx.doi.org/10.3389/fimmu.2021.729851

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