Cargando…
Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity
Multiple agents in the family Filoviridae (filoviruses) are associated with sporadic human outbreaks of highly lethal disease, while others, including several recently identified agents, possess strong zoonotic potential. Although viral glycoprotein (GP)-specific monoclonal antibodies have demonstra...
Autores principales: | Wirchnianski, Ariel S., Wec, Anna Z., Nyakatura, Elisabeth K., Herbert, Andrew S., Slough, Megan M., Kuehne, Ana I., Mittler, Eva, Jangra, Rohit K., Teruya, Jonathan, Dye, John M., Lai, Jonathan R., Chandran, Kartik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551868/ https://www.ncbi.nlm.nih.gov/pubmed/34721393 http://dx.doi.org/10.3389/fimmu.2021.729851 |
Ejemplares similares
-
Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors
por: Slough, Megan M., et al.
Publicado: (2019) -
Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses
por: Frei, Julia C., et al.
Publicado: (2016) -
Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion
por: Kleinfelter, Lara M., et al.
Publicado: (2015) -
Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection
por: Slough, Megan M., et al.
Publicado: (2023) -
Author Correction: Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection
por: Slough, Megan M., et al.
Publicado: (2023)