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IL-35 subunit EBI3 alleviates bleomycin-induced pulmonary fibrosis via suppressing DNA enrichment of STAT3

BACKGROUND: IL-35 subunit EBI3 is up-regulated in pulmonary fibrosis tissues. In this study, we investigated the pathological role of EBI3 in pulmonary fibrosis and dissected the underlying molecular mechanism. METHODS: Bleomycin-induced pulmonary fibrosis mouse model was established, and samples we...

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Detalles Bibliográficos
Autores principales: Chen, Donghong, Zheng, Guofeng, Yang, Qing, Luo, Le, Shen, Jinglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551952/
https://www.ncbi.nlm.nih.gov/pubmed/34711217
http://dx.doi.org/10.1186/s12931-021-01858-x