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Anti-inflammation and antimalarial profile of 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester as a low molecular intermediate for hybrid drug synthesis

A novel 1,2,4-triazole intermediate 5-pyridin-2-yl-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester was prepared by the reaction of N’-aminopiridyne-2-carboximidamine and an excess monoethyl oxalyl chloride and screened for biological activities. The compound was structurally characterized by nuclea...

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Detalles Bibliográficos
Autores principales: Eya’ane Meva, Francois, Prior, Timothy J., Evans, David J., Shah, Sachin, Tamngwa, Cynthia Fake, Belengue, Herschelle Guyenne Lagrange, Mang, Roland Emmanuel, Munro, Justin, Qahash, Tarrick, Llinás, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551956/
http://dx.doi.org/10.1007/s11164-021-04607-3